Ativan is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation of hospitalized patients, as well as sedation of aggressive patients.
Other Brand Names:Temesta, Alzapam, Lora
Generic Name: Lorazepam
- Acute seizures
- Recreational (ILLEGAL)
Availability: Lorazepam is available in 0.5-mg, 1-mg, and 2-mg tablets and in an injectable form.
- Allergy or hypersensitivity
- Severe respiratory failure
- Acute intoxication
- Acute narrow-angle glaucoma
- Sleep apnea
- Myasthenia gravis
- Pregnancy and breast feeding
- confusion, depressed mood, thoughts of suicide or hurting yourself
- hyperactivity, agitation, hostility
- feeling light-headed, fainting.
Less serious side effects may include:
- drowsiness, dizziness, tiredness
- blurred vision
- sleep problems (insomnia)
- muscle weakness, lack of balance or coordination
- amnesia or forgetfulness, trouble concentrating
- nausea, vomiting, constipation
- appetite changes
- skin rash
Black Box Warnings: In the United Kingdom, Ativan has carried a “black box” warning for decades. In the United States, it has not. You should not take Ativan if you have sleep apnea as it can be fatal.
Half-life: 10-20 hours
Withdrawal symptoms include headaches, anxiety, tension, depression, insomnia, restlessness, confusion, irritability, sweating, dysphoria, dizziness, derealization, depersonalization, numbness/tingling of extremities, hypersensitivity to light, sound, and smell, perceptual distortions, nausea, vomiting, diarrhea, appetite loss, hallucinations, delirium, seizures, tremor, stomach cramps, myalgia, agitation, palpitations, tachycardia, panic attacks, short-term memory loss, and hyperthermia. It takes approximately 18–36 hours for the benzodiazepine to remove itself from the body.
The risk and severity of withdrawal is increased with long-term use, use of high doses, abrupt or over-rapid reduction, among other factors. Short-acting benzodiazepines such as lorazepam are more likely to cause a more severe withdrawal syndrome compared to longer-acting benzodiazepines.